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article 2019 6 pages

Exercise-induced cardiac troponin elevation: An update on the evidence, mechanism and implications

Polly Baker, Todd Leckie, Derek Harrington, Alan Richardson

Journal
IJC Heart & Vasculature
DOI
10.1016/j.ijcha.2019.03.001
Population
runners
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Abstract

Purpose

We aimed at exploring whether cardiopulmonary fitness, echocardiographic measures and relative exercise intensity were associated with high-sensitivity cardiac troponin T (hs-TNT) rise and normalization following a marathon.

Methods

Nighty-eight participants (83 men, 15 women; 38.72 ± 3.63 years) were subjected to echocardiographic assessment and a cardiopulmonary exercise test (CPET) before the race. hs-TNT was measured before, immediately after and at 24, 48, 96, 144 and 192 h post-race. Speed and mean heart rate (HR) during the race were relativized to CPET values: peak speed (%VVMAX), peak HR (HR%MAX), speed and HR at the second ventilatory threshold (HR%VT2 and %VVT2).

Results

Hs-TNT increased from pre- to post-race (5.74 ± 5.29 vs. 50.4 ± 57.04 ng/L; p 

Description

This article reviews the implications of exercise-induced cardiac troponin elevation.