Abstract
Extracts derived from Indian frankincense (Boswellia serrata) effectively reduce the pain and swelling associated with osteoarthritis. It is unknown whether the anti-inflammatory and analgesic properties of B. serrata extend to muscle and joint pain resulting from high-impact eccentric exercise. This pilot study evaluated the efficacy of a standardized B. serrata extract LI51202F1 (SBS) to decrease soreness and improve recovery after repeated bouts of downhill running (DHR) compared to placebo (PLA). In total, 50 men (mean age 28 ± 4) were randomly allocated to consume 60 mg SBS or PLA once per day for 10 days (6 days before, the day of, and 3 days after DHR). On day 7, delayed soreness was induced by three 15-min DHR episodes on a 10% declined treadmill. Visual analog scale (VAS) scores of joint and muscle soreness, in addition to the maximal weight lifted for a one-repetition leg extension (1RM-LE) were assessed at baseline (pre-supplementation) and on days 8, 9, and 10. Blood and urine samples collected at baseline, before, and after DHR were analyzed for inflammation-related biomarkers. VAS scores significantly increased while muscle strength decreased from baseline measures after DHR regardless of group assignment (main effect of time p = 0.001). On day 10, the SBS group’s VAS scores were 8.0 ± 1.6 mm lower than the PLA group ( = 0.006). The SBS-supplemented subjects reported less knee joint pain after DHR than the PLA group ( , improves recovery and reduces soreness following high-impact eccentric exercise.
, Clinical Trial Registry of India (CTRI/2019/07/020323).
Description
The study investigates the effects of Boswellia serrata on muscle soreness and recovery.