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article 2013 8 pages

Exercise-Induced Changes in Iron Status and Hepcidin Response in Female Runners

Irena Auersperger, Branko Škof, Bojan Leskošek, Bojan Knap, Aleš Jerin, Mitja Lainscak

Journal
PLOS ONE
DOI
10.1371/journal.pone.0058090
Publication type
Research Article
Study type
observational study
Population
female runners
View on DOI ↗

Abstract

Background and Aims

Exercise-induced iron deficiency is a common finding in endurance athletes. It has been suggested recently that hepcidin may be an important mediator in this process.

Objective

To determine hepcidin levels and markers of iron status during long-term exercise training in female runners with depleted and normal iron stores.

Methods

Fourteen runners were divided into two groups according to iron status. Blood samples were taken during a period of eight weeks at baseline, after training and after ten days’ recovery phase.

Results

Of 14 runners, 7 were iron deficient at baseline and 10 after training. Hepcidin was lower at recovery compared with baseline (p

Description

The study investigates the impact of long-term exercise on iron status and hepcidin levels in female runners.