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article 2021 28 pages

Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials

Noah M. A. d’Unienville, Henry T. Blake, Alison M. Coates, Alison M. Hill, Maximillian J. Nelson, Jonathan D. Buckley

Journal
Journal of the International Society of Sports Nutrition
DOI
10.1186/s12970-021-00472-y
Publication type
Review Paper
Study type
systematic review
Population
well-trained males
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Abstract

Background

Increasing nitric oxide bioavailability may induce physiological effects that enhance endurance exercise performance. This review sought to evaluate the performance effects of consuming foods containing compounds that may promote nitric oxide bioavailability.

Methods

Scopus, Web of Science, Ovid Medline, EMBASE and SportDiscus were searched, with included studies assessing endurance performance following consumption of foods containing nitrate, L-arginine, L-citrulline or polyphenols. Random effects meta-analysis was conducted, with subgroup analyses performed based on food sources, sex, fitness, performance test type and supplementation protocol (e.g. duration).

Results

One hundred and eighteen studies were included in the meta-analysis, which encompassed 59 polyphenol studies, 56 nitrate studies and three L-citrulline studies. No effect on exercise performance following consumption of foods rich in L-citrulline was identified (SMD=-0.03, p=0.24). Trivial but significant benefits were demonstrated for consumption of nitrate and polyphenol-rich foods (SMD=0.15 and 0.17, respectively, p

Description

The review evaluates the effects of dietary compounds on endurance exercise performance.