article 2016 10 pages

Effects of High-Intensity Training of Professional Runners on Myocardial Hypertrophy and Subclinical Atherosclerosis

Célia Regina de Oliveira Bittencourt, Maria Cristina de Oliveira Izar, Valdir Lauro Schwerz, Rui Manuel dos Santos Póvoa, Henrique Andrade Rodrigues Fonseca, Marília Izar Helfenstein Fonseca, Henrique Tria Bianco, Carolina Nunes França, Carlos Eduardo dos Santos Ferreira, Francisco Antonio Helfenstein Fonseca

Journal: PLOS ONE
DOI: 10.1371/journal.pone.0166009
Publication type: Research Article
Study type: prospective study
Population: professional runners

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Abstract

To evaluate the effects of long-term exposure to high-intensity training among professional runners on cardiac hypertrophy and subclinical atherosclerosis.

Prospective study included runners of both sexes (n = 52) and age and gender matched controls (n = 57), without classical cardiovascular risk factors. Ventricular hypertrophy was quantified by echocardiography by linear method and carotid intima-media thickness (cIMT) by 2-D images obtained by ultrasonography. Endothelial function was evaluated by flow-mediated dilation (FMD). Steroid hormones were quantified by HPLC followed by LC-MS/MS. Higher left ventricular (LV) mass index was found in male athletes (p

Description

This study investigates the impact of high-intensity training on cardiac health in professional runners.