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article 2021 11 pages

The effects of dietary nitrate supplementation on endurance exercise performance and cardiorespiratory measures in healthy adults: a systematic review and meta-analysis

Chloe Gao, Saurabh Gupta, Taranah Adli, Winston Hou, Reid Coolsaet, Abigail Hayes, Kevin Kim, Arjun Pandey, Jacob Gordon, Gurneet Chahil, Emilie P. Belley-Cote, Richard P. Whitlock

Journal
Journal of the International Society of Sports Nutrition
DOI
10.1186/s12970-021-00450-4
Publication type
Systematic Review
Population
healthy adults
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Abstract

Background

Nitrate supplementation is thought to improve performance in endurance sports.

Objective

To meta-analyze studies evaluating the effect of nitrate supplementation on endurance sports performance among adults.

Data sources

We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, Web of Science and CINAHL without language restrictions.

Methods

We included studies that: 1) compared nitrate supplementation with placebo; 2) enrolled adults engaging in an endurance-based activity; and 3) reported a performance measure or surrogate physiologic outcome. We evaluated risk of bias using the Cochrane Collaboration tool and pooled data with a random-effects model. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to evaluate confidence in estimates.

Results

We included 73 studies (n = 1061). Nitrate supplementation improved power output (MD 4.6 watts, P 

Description

The study evaluates the effects of dietary nitrate on endurance performance.